Patients who survive intensive care often are weak, debilitated and with a poorer quality of life compared to their pre-morbid status. We are actively investigating methods to prevent weakness and loss of function in long stay intensive care patients. There are also many projects investigating the optimum delivery of standard procedures to ensure that the best quality of care is offered to intensive care patients.

Current projects

  • Optimal pattern of manual hyperinflation in the ventilated patient.  Paratz J, Thomas P, Savian C, Lipman J
  • A point prevalence survey of venous thromboembolism prophylaxis management in the critically ill and an epidemiological observational audit of venous thromboembolism prophylaxis management in critically ill patients with severe sepsis (VTE AUDIT). Gowardman J.
  • The clinical experience of nitric oxide use in the adult ICU at the RBWH. Boots R
  • Effectiveness of a continuous infusion intervention versus standard intermittent dosing of beta-lactam antibiotics in the treatment of severe sepsis. Lipman J, Webb S, Roberts J, Dulhunty J, Davis J, Gomersall C.
  • A randomised controlled trial of the effect of hydrocortisone on mortality in critically ill patients with septic shock (ADRENAL Study). Venkatesh B, Myburgh J, Finfer S, Webb S, Cohen J.
  • Assessment of Functional Adrenal Status in Patients with Septic Shock. Cohen J, Venkatesh B.
  • Developing a research base for intravenous peripheral catheter resites. The DRIP trial.  Rickard C, Webster J, Gowardman J, Wallis M, McCann D.
  • SAVED - Study of practices and complications associated with central venous and arterial catheterisation in an ICU population.  Gowardman J, Rickard C.
  • An exploratory study of perceived risks, benefits and barriers to the use of Selective Decontamination of the Digestive Tract in Australasian ICUs (SuDDICU). Seppelt I, Marshall A, Myburgh J, Lipman J, Francis J, Cuthbertson B, Glass P. Funder: ANZCA
  • Endothelin, a marker of severity in subarachnoid hemorrhage vasospasm. Bellapart J, Fourie C, Stuart J, Boots R, Paratz J.
  • Securing Arterial and Venous Devices Effectively in Hospitals: The SAVE Pilot Trial. Funder: RBWH Foundation Scholarship for H. Reynolds
  • Exogenous melatonin in critically ill patients: the impact on sleep and ICU psychosis. Bellapart J, Boots R, Zappala C, Paratz J, Morrison S, Brown M. Funder: RBWH
  • Inspiratory Muscle Training for ventilated patients. Bissett B, Paratz J, Boots R, Leditschke A.
  • i-PERFORM Trial-Mobilising the Critically Ill: Physiological and Functional Outcomes following Early Rehabilitation in Sepsis. Kayambu G, Paratz J.
  • Intravascular Device administration sets: Replacement after standard versus prolonged use (RSVP Trial). Rickard C, Wallis M, Young J, Gowardman J, Whitby M, Fraser J, McMillan D, Zhang L. Funder: NHMRC
  • A Real-time and Self-Adaptive Stream Data Analyser for Intensive Care Management. Zhang Y, Yi  X, He  J, Pang C, Steyn M. Funder: ARC
  • Exercise testing in the chronic critically ill patient. Paratz J, Stockton K, Boots R.
  • Low molecular weight heparin in critically ill trauma patients: a dosing study. O'Donoghue S, Lipman J, Udy A. Funder: RBWH
  • 11-β-hydroxysteroid dehydrogenases activity in critical illness.  Cohen J Funder: ANZCA
  • Investigation of the Cerebral Microcirculation after Head Injury. Bellapart J, Boots R, Fraser J, Maybauer M, Helps S. Funder: Brain Foundation, Defence Health Foundation, RBWH Foundation
  • Prevention of Ventilator Associated Pneumonia by Inhaled Heparin. Boots R, Paratz J, Lipman J, Paterson D, Roberts J. Funder: ANZICS, RBWH
  • Improving outcomes in sepsis. Boots R, Paratz J, Kenardy J, Mitchell G, Coyer F, Comans T. Funder: RBWH Foundation
  • Saving blood and money - introduction of laboratory testing guidelines and its effect on blood loss and cost of therapy in an intensive care unit. Dhanani J, Barnett A, Lipman J, Boots R, Ford M, Jarrett P. Funder: AusHSI Stimulus Grant
  • Augmented Renal Clearance in the Intensive Care Unit. Udy A, Lipman J, Roberts J, Boots R. Funder: RBWH Foundation
  • INFlammation and Augmented Renal Clearance in Traumatic brain injury (INFARCT) Study. Udy A, Lipman J, Jarrett P. Funder: RBWH
  • Determinants of Urinary Output Response to Intravenous Frusemide in Patients with Acute Kidney Injury. Ho K, Corcoran T, Lipman J, Roberts J, Barden A, Mori T.  Funder: ANZCA
  • Pre-clinical testing of the AutoStart Burette for use with intravascular devices: comparison with standard burette technology. Rickard C, Webster J, McMillan D, Wallis S, Zhang L, Marsh N. Funder: Griffith University Industry Collaborative Scheme
  • Detection of secretion retention in ventilated patients - Paratz J, Jones A, Thomas P, Li Bassi G, Torres A, Ntoumenopoulos G.
  • Assessment of the Microcirculation in Shocked Critically Unwell Patients during the First 24 hours of Resuscitation. Holley A, Udy A, Boots R, Paratz J, O'Donoghue S, Douglas A, Roberts J, Hurn C, Lukin B, Lipman J. Funder: RBWH Foundation/Wormald

Researchers