Dr Anthony Holley
BSc MBBCh DipPaeds DipDHM FACEM FCICM
Senior Intensivist
Royal Brisbane and Women's Hospital
Academic Title-Senior Lecturer
Royal Brisbane Clinical Unit

Researcher biography
Dr Holley is an intensivist at RBWH and a senior lecturer with UQ Medical School. He serves on the ANZICS National Executive and is a CICM fellowship examiner. Anthony is a supervisor of ICU training at the RBWH and a representative for the NBA Critical Care Group in developing the Australian Patient Blood Management Guidelines. Anthony is a serving Commander in the Royal Australian Navy Reserve and has deployed extensively.
Book Chapters
Holley, Anthony D. (2016). Management of the critically ill burns patient. Trauma and combat critical care in clinical practice. (pp. 277-306) edited by Sam D. Hutchings. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-28758-4_12
Reade, M. C. and Holley, A. D. (2012). A new understanding of coagulopathy in trauma: potential therapeutic implications. Annual update in intensive care and emergency medicine 2012. (pp. 689-698) edited by Jean-Louis Vincent. Berlin, Germany: Springer. doi: 10.1007/978-3-642-25716-2_62
Journal Articles
Reade, Michael C., Marks, Denese C., Bellomo, Rinaldo, Deans, Renae, Faulke, Daniel J., Fraser, John F., Gattas, David J., Holley, Anthony D., Irving, David O., Johnson, Lacey, Pearse, Bronwyn L., Royse, Alistair G., Wong, Janet, Bellomo, Rinaldo, Weinberg, Laurence, Eastwood, Glenn, Peck, Leah, Young, Helen, Sidiropoulos, Sofia, Baulch, Sarah, Dalyell, Amanda, Kolar, Diana, Martinelli, Tony, Reidy, Yvonne, Caldwell, Natalie, Royse, Alistair, Tivendale, Lynda, Bisignano, Maria, Hausler, Michael ... Irving, David (2019). A randomized, controlled pilot clinical trial of cryopreserved platelets for perioperative surgical bleeding: the CLIP‐I trial. Transfusion, 59 (9), 2794-2804. doi: 10.1111/trf.15423
Yuan, Yin, Mediwake, Heshani, Bokhari, Syed W., Holley, Anthony and Lane, Steven W. (2019). Acute promyelocytic leukaemia with marked symptomatic hyperleucocytosis: images in haematology. British Journal of Haematology, 186 (5), 649-649. doi: 10.1111/bjh.16016
Vellinga, N. A.R., Boerma, E. C., Koopmans, M., Donati, A., Dubin, A., Shapiro, N. I., Pearse, R. M., van der Voort, P. H.J., Dondorp, A. M., Bafi, Tony, Fries, M., Akarsu-Ayazoglu, Tulin, Pranskunas, A., Hollenberg, Steven, Balestra, Gianmarco, van Iterson, M., Sadaka, Farid, Minto, G., Aypar, U., Hurtado, F. J., Martinelli, G., Payen, D., van Haren, Frank, Holley, A., Gomez, H., Mehta, R., Rodriguez, A. H., Ruiz, C., Canales, H. S. ... Ayazoglu-Akarsu, T. (2017). Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: A microSOAP post hoc analysis. Critical Care, 21 (1) 255. doi: 10.1186/s13054-017-1842-7
Ho, Kwok M., Rao, Sudhakar, Honeybul, Stephen, Zellweger, Rene, Wibrow, Bradley, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Geelhoed, Elizabeth and Corcoran, Tomas (2017). Detailed assessment of benefits and risks of retrievable inferior vena cava filters on patients with complicated injuries: the da Vinci multicentre randomised controlled trial study protocol. Bmj Open, 7 (7) e016747, e016747. doi: 10.1136/bmjopen-2017-016747
Winearls, James, Wullschleger, Martin, Wake, Elizabeth, Hurn, Catherine, Furyk, Jeremy, Ryan, Glenn, Trout, Melita, Walsham, James, Holley, Anthony, Cohen, Jeremy, Shuttleworth, Megan, Dyer, Wayne, Keijzers, Gerben, Fraser, John F., Presneill, Jeffrey and Campbell, Don (2017). Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial. Trials, 18 (1) 241, 241. doi: 10.1186/s13063-017-1980-x
Winearls, James, Campbell, Don, Hurn, Catherine, Furyk, Jeremy, Ryan, Glenn, Trout, Melita, Walsham, James, Holley, Anthony, Shuttleworth, Megan, Dyer, Wayne, Keijzers, Gerben, Presneill, Jeff, Fraser, John F. and Wullschleger, Martin (2017). Fibrinogen in traumatic haemorrhage: a narrative review. Injury, 48 (2), 230-242. doi: 10.1016/j.injury.2016.12.012
Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. Journal of Critical Care, 35, 231-239. doi: 10.1016/j.jcrc.2016.06.022
Bandeshe, Hiran, Boots, Rob, Dulhunty, Joel, Dunlop, Rachael, Holley, Anthony, Jarrett, Paul, Gomersall, Charles D., Lipman, Jeff, Lo, Thomas, O'Donoghue, Steven, Paratz, Jenny, Paterson, David, Roberts, Jason A., Starr, Therese, Stephens, Di, Stuart, Janine, Thomas, Jane, Udy, Andrew and White, Hayden (2016). Is inhaled prophylactic heparin useful for prevention and management of pneumonia in ventilated ICU patients?. The IPHIVAP investigators of the Australian and New Zealand Intensive Care Society Clinical Trials Group. Journal of Critical Care, 34, 95-102. doi: 10.1016/j.jcrc.2016.04.005
O'Callaghan D., Holley A. and Lipman J. (2015). From the intensive care bed: we need to hear and listen. Intensive Care Medicine, 41 (5), 921-922. doi: 10.1007/s00134-014-3614-z
Vellinga, Namkje A. R., Boerma, E. Christiaan, Koopmans, Matty, Donati, Abele, Dubin, Arnaldo, Shapiro, Nathan I., Pearse, Rupert M., Machado, Flavia R., Fries, Michael, Akarsu-Ayazoglu, Tulin, Pranskunas, Andrius, Hollenberg, Steven, Balestra, Gianmarco, van Iterson, Mat, van der Voort, Peter H. J., Sadaka, Farid, Minto, Gary, Aypar, Ulku, Hurtado, F. Javier, Martinelli, Giampaolo, Payen, Didier, van Haren, Frank, Holley, Anthony, Pattnaik, Rajyabardhan, Gomez, Hernando, Mehta, Ravindra L., Rodriguez, Alejandro H., Ruiz, Carolina, Canales, Hector S. ... for the microSOAP Study Group (2015). International study on microcirculatory shock occurrence in acutely Ill patients. Critical Care Medicine, 43 (1), 48-56. doi: 10.1097/CCM.0000000000000553
Vermeir, Julie, Holley, Anthony and Lipman, Jeffrey (2015). “Not out of the woods”—a wife’s perspective: bedside communication. Intensive Care Medicine, 42 (3), 446-447. doi: 10.1007/s00134-015-4035-3
Holley, Anthony D. and Reade, Michael C. (2013). The 'procoagulopathy' of trauma: too much, too late?. Current Opinion in Critical Care, 19 (6), 578-586. doi: 10.1097/MCC.0000000000000032
Holley, Anthony, Marks, Denese, Johnson, L., Reade, Michael C., Badloe, J. and Noorman, F. (2013). Frozen blood products: clinically effective and potentially ideal for remote Australia. Anaesthesia and Intensive Care, 41 (1), 10-19. doi: 10.1177/0310057x1304100104
Holley, Anthony D., Weber, Daniel J. and Reade, Michael C. (2012). A battlefield occupational risk not to be ignored. Medical Journal of Australia, 197 (6), 331-331. doi: 10.5694/mja12.10694
Townell, Nicola J., Munckhof, Wendy J., Nimmo, Graeme, Bannan, Aiveen, Holley, Anthony, Daniel, Abhay, Bennett, Cameron, Coulter, Christopher and Looke, David F. M. (2012). Community-associated methicillin-resistant Staphylococcus aureus endocarditis 'down under': Case series and literature review. Scandinavian Journal of Infectious Diseases, 44 (7), 536-540. doi: 10.3109/00365548.2012.664779
Holley, Anthony, Lukin, William, Paratz, Jennifer, Hawkins, Tracey, Boots, Robert and Lipman, Jeffrey (2012). Review article: Part two: Goal-directed resuscitation - Which goals? Perfusion targets. Emergency Medicine Australasia, 24 (2), 127-135. doi: 10.1111/j.1742-6723.2011.01515.x
Holley, Anthony, Lukin, William, Paratz, Jennifer, Hawkins, Tracey, Boots, Roberts and Lipman, Jeffrey (2012). Review article: Part one: Goal-directed resuscitation - Which goals? Haemodynamic targets. Emergency Medicine Australasia, 24 (1), 14-22. doi: 10.1111/j.1742-6723.2011.01516.x
Holley, A. D., Osland, E., Barnes, J., Krishnan, A. and Fraser, J. F. (2011). Scurvy: Historically a plague of the sailor that remains a consideration in the modern intensive care unit. Internal Medicine Journal, 41 (3), 283-285. doi: 10.1111/j.1445-5994.2010.02413.x
Douglas, A. E., Holley, A., Udy, A., Lipman, J., Gomersall, C. D., Joynt, G, Freebairn, R. C. and Boots, R. J. (2010). Can learning to sustain life be BASIC? Teaching for the initial management of the critically ill in Australia and New Zealand. Anaesthesia and Intensive Care, 38 (6), 1043-1051.
Boots, Robert J., Udy, Andrew, Holley, Anthony and Lipman, Jeffrey (2010). Preventive strategies for ventilator associated pneumonia. Current Respiratory Medicine Reviews, 6 (4), 238-252. doi: 10.2174/157339810793563758
McNeill, G, Holley, A and Lipman, J (2009). Emphysematous pyelonephritis: an unusual complication of blunt abdominal trauma. Critical Care and Resuscitation, 11 (4), 269-271.
Holley, A, Udy, A and Lipman, J (2009). The microcirculation, regional blood flow and tissue oxygenation: will new technologies drive new resuscitation goals?. Anaesthesia and Intensive Care, 37 (5), 700-702.
Holley, A and Boots, R (2009). Management of acute severe and near-fatal asthma. Emergency Medicine Australasia, 21 (4), 259-268. doi: 10.1111/j.1742-6723.2009.01195.x
Holley, Anthony, Dulhunty, Joel, Blot, Stijn, Lipman, Jeffrey, Lobo, Suzana, Dancer, Craig, Rello, Jordi and Dimopoulos, George (2009). Temporal trends, risk factors and outcomes in albicans and non-albicans candidaemia: an international epidemiological study in four multidisciplinary intensive care units. International Journal of Antimicrobial Agents, 33 (6), 554.e1-554.e7. doi: 10.1016/j.ijantimicag.2008.10.035
Holley, Anthony D (2008). Synthetic blood products: science fiction or coming to an ICU near you?. Critical Care & Resuscitation, 10 (3), 253-256.
Michaela Cartner, Anthony Holley and Anthony Allworth (2008). False impressions from clear cerebrospinal fluid and a normal computed tomography scan: The pressure is still on for a diagnosis. Emergency Medicine Australasia, 20 (3), 276-279. doi: 10.1111/j.1742-6723.2008.01095.x
Holley, A. D., Green, S. and Davoren, P. (2007). Extreme hypernatraemia: A case report and brief review. Critical Care and Resuscitation, 9 (1), 55-58.
Holley, A., Cartner, M. and Lipman, J. (2007). Acute respiratory distress in a bleomycin primed patient: a new use for nitric oxide. Anaesthesia and Intensive Care, 35 (1), 86-90. doi: 10.1177/0310057x0703500112
Munckhof, WJ, Runnegar, N, Gray, TJ, Taylor, C, Palmer, C and Holley, A (2007). Two rare severe and fulminant presentations of Q fever in patients with minimal risk factors for this disease. Internal Medicine Journal, 37 (11), 775-778. doi: 10.1111/j.1445-5994.2007.01489.x
Holley, Anthony David and Ziegenfuss, Marc (2006). Levosimendan: A new option in acute cardiac failure. Emergency Medicine Australasia, 18 (5-6), 505-509. doi: 10.1111/j.1742-6723.2006.00871.x